Wednesday, May 16, 2012

Endocrinology: The Core of Hormones



            Whenever we encounter the word "Endocrinology" maybe the first thing that comes up our mind is the word hormone. Hormones are stereotypically generalized as an important ingredient for growth, however, there are other purposes where hormones are involved such as maintaining the chemical level in the bloodstream to maintain homeostasis. They are produced by different glands in our body whereby an integrated system succeeded which is the Endocrine System.


              Here is a video of a hormonal imbalance disorder that intrigues me a lot. It is known as hirsutism or virilism which mostly affects us females.




            
               Isn't it difficult for a woman to be unpleasantly looking? Of course it is hard. Every  women wants to be attractive in everybody's eyes. This disorder is the excessive growth of hair in women which can be in the facial area, beard area, neck, chest wall and upper abdomen which makes them look like a man. It involves the overacting work of the androgens to female's hair follicle that causes too much hair growth. In some cases a newborn baby girl can have an external organ that looks like a mixture of a male organ, this is called female pseudohermaphrodism. I can't imagine how hard for females who have this kind of illness survive everyday knowing that they cannot enjoy a normal life.




Image Credit:http://acner.org/alternative-treatments-for-hirsutism/
Image Credit: http://www.sciencephoto.com/media/257353/enlarge
               


              Endocrinology, a branch of medicine and biology which is concerned with the study of the endocrine system, its function, its secretions, and the disorders involved. Robert K. G. Temple, he said that the study of endocrinology first began in China, in which researchers used human urine to isolate pituitary and sex hormones. Some articles in Chinese Medical Books way back in 1110 clarified that saponification was used to extract hormones.


Endocrine System

Image Credit: https://www.google.com.ph/search?hl=fil&q=endocrine%20system&btnK=&um=1&ie=UTF-8&tbm=isch&source=og&sa=N&tab=wi&ei=tHqzT-eiLsufiQfH14j1CA&biw=1024&bih=499&sei=vHqzT7eKNKqSiQfs8PjrBg



            The study of endocrinology involves a broad spectrum of its learning, and though every organ system secretes and retorts to hormones endocrinology focuses specifically on endocrine organs. The organs which centers hormone secretions are the endocrine organs such as adrenals, ovaries, pancreas, pituitary, testes, and thyroid. An endocrinologist greatest role is to specialized treating disorders of the endocrine system like hyperthyroidism, Addison’s disease and Cushing's syndrome. Many people suffer from these maladies that are why it is categorically important to know more in this field of science.

Endocrine Organs: Hormones and their functions:
  • Adrenal Gland 

     1. Cortisol- known as the stress hormone


  • Ovaries
  1. Inhibin- regulates FSH
  2. Estrogen-(estridiol, estriol, estrone) for growth promotion elasticity of connective tissue and preserve bone mass
  3. Progesterone- for the maintenance of endometrium in penetration for pregnancy
  4. Testosterone- acts as libido

    • Pancreas

    1. Insulin - lowers blood sugar level
    2. Glucagon- raises blood sugar level

    • Pituitary Gland

    1. Adenocorticotrophic hormone - for production of corticosol
    2. Follicle Stimulating Hormone - stimulates maturation of ovarian follicles
    3. Growth Hormone - it acts on various tissues to promote growth
    4.  Luteinizing Hormone - it induces ovulation and produces estrogen
    5. Melanocyte Stimulating Hormone - it stimulates the tone of the skin
    6. Prolactin - for production of milk for lactating females
    7. Thyroid Stimulating Hormone - transmits signal to the thyroid gland for the production of thyroxin

    • Testis
    1. Dihydrotestosterone - important for secondary male characterictics
    2. Testosterone- sperm production and libido
    • Thyroid

    1. Tri- iodothyronine and thyroxine- for the regulation of metabolism, development of reproductive tract and brain.




    Book reference: Henry's Clinical Diagnosis and Management by Laboratory Methods 21st Edition
                                      http://www.emcom.ca/primer/list.shtml
                                      http://health.yahoo.net/galecontent/adrenal-virilism